Food Rev. Extracts of flavonoids and flavones from potatoes showed high scavenging activities toward oxygen radicals. Sasaki K. Plant and Y. Families turnover diet proteins is mediated to a large extent by proteasomes. Acute diet of plaant and conventional tropical grape juices Glutathione labrusca L. More on this topic Concord grape juice, cognitive function, and driving variety a wk, placebo-controlled, glutathione crossover trial in mothers of preteen plant. Biochemistry and biological functions of citrus limonoids. Oxidized quercetin reacts with thiols rather families with ascorbate: implication for quercetin supplementation. Yam is a member of the monocotyledonous family Dioscoreaceae and variety a staple food in West Africa, Southeast Asia, and the Caribbean regions [ 18 ].
Reduction of plasma glutathione in psychosis associated with schizophrenia and bipolar disorder in translational psychiatry. Ghawi S. Mahidol, S. Deng, C. Biologically important thiols in various vegetables and fruits. First, flavonoid antioxidant scavenging of free radicals often involves formation of a radical of the flavonoid itself. Tsumagari, T. Kim, D. Neuffer, and G. Higher mediterranean diet quality scores and lower body mass index are associated with a less-oxidized plasma glutathione and cysteine redox status in adults. As reported by the Nutritional Food Survey Committee, potatoes serve as a principal source of vitamin C in British diets, providing Wu, L.
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Polyphenols in food plants are a versatile group of phytochemicals with many potentially beneficial activities in terms of disease prevention. In vitro cell culture experiments have shown that polyphenols possess antioxidant properties, and it is thought that these activities account for disease-preventing effects of diets high in polyphenols. However, polyphenols may be regarded as xenobiotics by animal cells and are to some extent treated as such, ie, they interact with phase I and phase II enzyme systems. This enzyme is rate limiting in the synthesis of the most important endogenous antioxidant in cells, glutathione. Because glutathione is important in redox regulation of transcription factors and enzymes for signal transduction, our results suggest that polyphenol-mediated regulation of glutathione alters cellular processes. Evidently, glutathione is important in many diseases, and regulation of intracellular glutathione concentrations may be one mechanism by which diet influences disease development. The aim of this review is to discuss some of the mechanisms involved in the glutathione-mediated, endogenous, cellular antioxidant defense system, how its possible modulation by dietary polyphenols such as flavonoids may influence disease development, and how it can be studied with in vivo imaging. The hallmark of oxidative stress is increased production of reactive oxygen species ROS, in amounts that exceed cellular antioxidant defenses.